Control of KCa Channels by Calcium Nano/Microdomains

Control of KCa Channels by Calcium Nano/Microdomains

Transient elevations in cytoplasmic Ca(2+) trigger a multitude of Ca(2+)-dependent processes in CNS neurons and many other cell types. The specificity, speed, and reliability of these processes is achieved and ensured by tightly restricting Ca(2+) signals to very local spatiotemporal domains, "Ca(2+) nano- and microdomains," that are centered around Ca(2+)-permeable channels. This arrangement r...

control of the optical properties of nanoparticles by laser fields

در این پایان نامه، درهمتنیدگی بین یک سیستم نقطه کوانتومی دوگانه(مولکول نقطه کوانتومی) و میدان مورد مطالعه قرار گرفته است. از آنتروپی ون نیومن به عنوان ابزاری برای بررسی درهمتنیدگی بین اتم و میدان استفاده شده و تاثیر پارامترهای مختلف، نظیر تونل زنی(که توسط تغییر ولتاژ ایجاد می شود)، شدت میدان و نسبت دو گسیل خودبخودی بر رفتار درجه درهمتنیدگی سیستم بررسی شده اشت.با تغییر هر یک از این پارامترها، در...

Calcium Channels Are Models of Self-Control

When Ca2+ ions fl ow through the pore of an individual voltage-gated Ca2+ channel, they act back on the channel they’ve passed through and alter subsequent Ca2+ fl ow. Such local, almost instantaneous regulation involves both positive and negative feedback mechanisms: Ca2+-dependent facilitation (CDF) and Ca2+-dependent inactivation (CDI), respectively. Indeed, some types of Ca2+ channel are ca...

Identification of calcium channels that control neurosecretion.

Morphine induces preconditioning via activation of mitochondrial KCa channels

PURPOSE Mitochondrial calcium sensitive potassium (mK(Ca)) channels are involved in cardioprotection induced by ischemic preconditioning. In the present study we investigated whether morphine-induced preconditioning also involves activation of mK(Ca) channels. METHODS Isolated rat hearts (six groups; each n = 8) underwent global ischemia for 30 min followed by a 60-min reperfusion. Control an...